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Yongcheng Song Selected Research

SEC Translocation Channels

1/2022A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth.
1/2021Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth.

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Yongcheng Song Research Topics

Disease

20Neoplasms (Cancer)
07/2022 - 04/2004
10Leukemia
01/2022 - 10/2011
5Glioma (Gliomas)
04/2022 - 06/2013
4Breast Neoplasms (Breast Cancer)
01/2020 - 07/2014
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018 - 06/2013
3Dengue (Dengue Fever)
12/2021 - 01/2019
3Infections
01/2013 - 03/2008
3Bone Resorption
11/2006 - 01/2004
2Hematologic Neoplasms (Hematological Malignancy)
07/2022 - 01/2020
2African Trypanosomiasis (Nagana)
01/2006 - 09/2005
1Carcinogenesis
01/2022
1Flavivirus Infections
11/2021
1Fibrosis (Cirrhosis)
12/2020
1Hypertrophy
12/2020
1Infarction (Infarctions)
12/2020
1Myocardial Infarction
12/2020
1Zika Virus Infection
01/2019
1Glioblastoma (Glioblastoma Multiforme)
01/2018
1Squamous Cell Carcinoma of Head and Neck
05/2016
1Caliciviridae Infections
01/2016
1Prostatic Neoplasms (Prostate Cancer)
12/2014
1Toxoplasmosis
04/2013
1Dehydration (Water Stress)
06/2012
1Chagas Disease (American Trypanosomiasis)
01/2006

Drug/Important Bio-Agent (IBA)

14Pharmaceutical PreparationsIBA
07/2022 - 09/2012
10Histones (Histone)IBA
07/2022 - 10/2011
7MethyltransferasesIBA
01/2021 - 10/2011
6Biological ProductsIBA
07/2022 - 01/2016
5Lysine (L-Lysine)FDA Link
07/2022 - 11/2014
5Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
04/2022 - 06/2013
5Proteins (Proteins, Gene)FDA Link
01/2021 - 04/2009
5EnzymesIBA
01/2016 - 01/2006
4Diphosphonates (Bisphosphonates)IBA
04/2009 - 01/2004
3Peptide Hydrolases (Proteases)FDA Link
12/2021 - 01/2019
3Estrogen ReceptorsIBA
01/2020 - 07/2014
3Small Interfering RNA (siRNA)IBA
01/2020 - 07/2014
2Proteolysis Targeting ChimeraIBA
01/2022 - 01/2020
2SEC Translocation ChannelsIBA
01/2022 - 01/2021
2Transcription Factors (Transcription Factor)IBA
01/2021 - 01/2018
2Oncogene Proteins (Oncogene Protein)IBA
01/2021 - 01/2020
2Peptides (Polypeptides)IBA
01/2021 - 05/2016
2Oxidoreductases (Dehydrogenase)IBA
09/2015 - 10/2014
2isocitric acid (isocitrate)IBA
09/2015 - 10/2014
2AcidsIBA
10/2014 - 06/2013
2Phosphorus (Red Phosphorus)IBA
09/2004 - 01/2004
1SirtuinsIBA
04/2022
1RNA (Ribonucleic Acid)IBA
04/2022
1Eukaryotic Initiation Factor-2 (EIF 2)IBA
04/2022
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
04/2022
1Adrenergic Agents (Adrenergic Drugs)IBA
04/2022
1Cyclin TIBA
01/2022
1PeptidomimeticsIBA
01/2021
1Steroid Receptors (Steroid Receptor)IBA
12/2020
14- ethyl- 2,6- bispyridin- 3- ylmethylenecyclohexanoneIBA
12/2020
1snake venom protein C activatorIBA
01/2020
1Estrogens (Estrogen)FDA Link
01/2020
1Antiviral Agents (Antivirals)IBA
01/2019
1Betamethasone (Celestone)FDA Link
01/2018
1GlucocorticoidsIBA
01/2018
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2018
1LigandsIBA
05/2016
1CytokinesIBA
05/2016
1InterferonsIBA
01/2016
1DNA Methyltransferase 3AIBA
01/2016
1Androgen Receptors (Androgen Receptor)IBA
12/2014
1enzalutamideIBA
12/2014
1abirateroneIBA
12/2014
1calcein AMIBA
11/2014
1fluorexon (calcein)IBA
11/2014
1AdenosylhomocysteinaseIBA
11/2014
13-deazaneplanocinIBA
11/2014
1Ketoglutaric Acids (Ketoglutaric Acid)IBA
10/2014
1Fulvestrant (Faslodex)FDA Link
07/2014
1Estrogen Receptor alphaIBA
07/2014
1TamoxifenFDA LinkGeneric
07/2014
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2014
1Mitoxantrone (Novantrone)FDA LinkGeneric
01/2014
1Etoposide (VP 16)FDA LinkGeneric
01/2014
1DNA (Deoxyribonucleic Acid)IBA
01/2014
1Histone MethyltransferasesIBA
05/2013
1isopreneIBA
04/2013
1Mevalonic Acid (Mevalonate)IBA
04/2013
1Anti-Infective Agents (Microbicides)IBA
01/2013
1Anti-Bacterial Agents (Antibiotics)IBA
01/2013
1MetalsIBA
06/2012
1TransferasesIBA
04/2009
1prenylIBA
12/2008
1Diphosphates (Pyrophosphates)IBA
12/2008
1CholesterolIBA
03/2008
1staphyloxanthinIBA
03/2008
1Immunologic Factors (Immunomodulators)IBA
11/2006
1HexokinaseIBA
01/2006
1PyrophosphatasesIBA
09/2005
1GeranyltranstransferaseIBA
04/2005
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
09/2004

Therapy/Procedure

9Therapeutics
04/2022 - 01/2004
2Drug Therapy (Chemotherapy)
01/2014 - 09/2004
1Radiotherapy
05/2016
1Castration
12/2014
1Aftercare (After-Treatment)
12/2014